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The deference between α-Arbutin and β-Arbutin
时间:2015-04-17 16:58 来源:未知
The deference between α-Arbutin and β-Arbutin
Chinese Name | α-Arbutin | β-Arbutin |
INCI Name | Alpha-Arbutin | Arbutin |
EU-Labeling Name | Alpha-Arbutin | Arbutin |
Chemistry | 4-hydroxyphenyl-α-D-glucopyranoside | P-hydroxy phenyl - β -D- glucopyranoside |
CAS No. | 84380-01-8 | 497-76-7 |
EINECS No. | 440-470-8 | 207-850-3 |
Melting Point | 198-201oC | 198-201oC |
Specific rotation | (a)20D=+174.0-+186.0 | (a)20D=-66-+2 |
Different Efficacy and Safety
ALPHA-ARBUTIN exhibits impressive in-vitro tyrosinase inhibition on human cell lysates compared to Beta-Arbutin. According to the test result from Inhibition Test of Tyrosine and B16 cell, it indicates that ALPHA-ARBUTIN has 10x more effective than β-Arbutin.
Commonly, the dosage to use β-Arbutin is 3% for cosmetic. If reducing the dosage,skin lightening effect is much less. But rising up the dosage will bring in irritation on skin. Contrarily, ALPHA-ARBUTIN exhibit impressive in-vitro tyrosinase inhibition on human cells, which brings in superior skin whitening efficacy without side effects.
Different MFG Methods
There are 3 ways to produce β-Arbutin including botanical extract,plant cell cultures,chemosynthesis. ALPHA-ARBUTIN can be only produced via Biosynthesis.
Luckerkong Biotech adopts advanced international biotechnology to make ALPHA-ARBUTIN, offers higher quality and stability.